Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 7014 associations (154 cell types, 4254 gene symbols, 28 tissues); Last updated: 19/02/2019 18:01:34 CET

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Description: Alpha cells are endocrine cells in the pancreatic islets of the pancreas. They make up to 20% of the human islet cells synthesizing and secreting the peptide hormone glucagon, which elevates the glucose levels in the blood.

Gene expression markers for Alpha cells

Species Official gene symbol UI Sensitivity Marker count Cell type Germ layer Organ Aliases Product description Disease Action
Mm Hs GTF2E2 0.075 0.034 1 Alpha cells Endoderm Pancreas TFIIE-B,TF2E2 general transcription factor IIE subunit 2 flag
Mm Hs STARD10 0.062 0.044 3 Alpha cells Endoderm Pancreas NY-CO-28,CGI-52,PCTP2,SDCCAG28 StAR related lipid transfer domain containing 10 flag
Mm Hs CHGA 0.058 0.04 5 Alpha cells Endoderm Pancreas chromogranin A flag
Mm Hs RESP18 0.05 0.013 3 Alpha cells Endoderm Pancreas regulated endocrine specific protein 18 flag
Mm Hs TTR 0.043 0.076 6 Alpha cells Endoderm Pancreas HsT2651,CTS,PALB,CTS1 transthyretin Yflag
Mm Hs PCSK2 0.035 0.038 4 Alpha cells Endoderm Pancreas SPC2,NEC2 proprotein convertase subtilisin/kexin type 2 flag
Mm Hs SYT13 0.034 0.059 2 Alpha cells Endoderm Pancreas KIAA1427 synaptotagmin 13 flag
Mm Hs CLDN4 0.031 0.09 4 Alpha cells Endoderm Pancreas CPE-R,WBSCR8,hCPE-R,CPETR,CPETR1 claudin 4 flag
Mm Hs NKX6-2 0.031 0 3 Alpha cells Endoderm Pancreas NKX6B,GTX,NKX6.1 NK6 homeobox 2 flag
Mm Hs GCH1 0.026 0.056 1 Alpha cells Endoderm Pancreas GTPCH1,DYT5a,GCH,DYT5,DYT14 GTP cyclohydrolase 1 Yflag
Mm Hs SLC38A5 0.024 0.084 2 Alpha cells Endoderm Pancreas SN2,JM24 solute carrier family 38 member 5 flag
Mm Hs ARX 0.023 0.007 3 Alpha cells Endoderm Pancreas ISSX,CT121,EIEE1,MRXS1,PRTS,MRX76,MRX54,MRX43,MRX36,MRX29,MRX32,MRX33,MRX38,MRX87 aristaless related homeobox Yflag
Mm Hs TM4SF4 0.016 0.165 6 Alpha cells Endoderm Pancreas il-TMP transmembrane 4 L six family member 4 flag
Mm Hs GCG 0.016 0 2 Alpha cells Endoderm Pancreas GLP2,GRPP glucagon flag
Mm Hs SCGN 0.015 0.157 3 Alpha cells Endoderm Pancreas SECRET,DJ501N12.8,SEGN,CALBL secretagogin, EF-hand calcium binding protein flag
Mm Hs FFAR2 0.011 0.182 2 Alpha cells Endoderm Pancreas FFA2R,GPR43 free fatty acid receptor 2 flag
Mm Hs PPY 0.01 0 3 Alpha cells Endoderm Pancreas PNP pancreatic polypeptide flag
Mm Hs CRYBA2 0.009 0.299 1 Alpha cells Endoderm Pancreas crystallin beta A2 Yflag
Mm Hs PCSK1 0.008 0.006 3 Alpha cells Endoderm Pancreas PC1,NEC1 proprotein convertase subtilisin/kexin type 1 Yflag
Mm Hs PRRG2 0.008 0.237 1 Alpha cells Endoderm Pancreas PRGP2 proline rich and Gla domain 2 flag
Mm Hs NKX6-1 0.007 0 4 Alpha cells Endoderm Pancreas Nkx6.1,NKX6A NK6 homeobox 1 flag
Mm Hs PYY 0.006 0.261 2 Alpha cells Endoderm Pancreas PYY1 peptide YY flag
Mm Hs KCNK16 0.006 0.464 2 Alpha cells Endoderm Pancreas K2p16.1,TALK-1,TALK1 potassium two pore domain channel subfamily K member 16 flag
Mm Hs POU3F4 0.004 0.2 2 Alpha cells Endoderm Pancreas BRN4,OTF9,DFNX2,DFN3 POU class 3 homeobox 4 Yflag
Mm Hs NKX2-2 0.003 0 6 Alpha cells Endoderm Pancreas NKX2.2,NKX2B NK2 homeobox 2 flag
Mm Hs GLP1R 0 0 1 Alpha cells Endoderm Pancreas GLP-1R glucagon like peptide 1 receptor flag

Datasets with computationally identified Alpha cells

SRA SRS tissue cluster cell type p-value FDR View
SRA701877 SRS3279684 Pancreatic islets 1 Alpha cells 8.77E-7 1.45E-4 view data
SRA701877 SRS3279684 Pancreatic islets 2 Alpha cells 1.81E-7 3.49E-5 view data
SRA701877 SRS3279684 Pancreatic islets 3 Alpha cells 7.75E-12 8.95E-9 view data
SRA701877 SRS3279684 Pancreatic islets 6 Alpha cells 6.28E-9 1.81E-6 view data
SRA701877 SRS3279684 Pancreatic islets 8 Alpha cells 2.40E-6 3.46E-4 view data
SRA701877 SRS3279684 Pancreatic islets 9 Alpha cells 1.81E-6 2.78E-4 view data
SRA701877 SRS3279684 Pancreatic islets 11 Alpha cells 9.34E-11 5.39E-8 view data
SRA701877 SRS3279685 Pancreatic islets 1 Alpha cells 9.64E-7 1.35E-4 view data
SRA701877 SRS3279685 Pancreatic islets 6 Alpha cells 1.27E-7 2.44E-5 view data
SRA701877 SRS3279686 Pancreatic islets 0 Alpha cells 4.11E-6 5.14E-4 view data
SRA701877 SRS3279686 Pancreatic islets 5 Alpha cells 8.59E-10 2.15E-7 view data
SRA701877 SRS3279687 Pancreatic islets 1 Alpha cells 2.69E-7 3.85E-5 view data
SRA701877 SRS3279687 Pancreatic islets 6 Alpha cells 1.38E-8 2.77E-6 view data
SRA701877 SRS3279687 Pancreatic islets 10 Alpha cells 8.75E-8 1.46E-5 view data
SRA701877 SRS3279688 Pancreatic islets 0 Alpha cells 4.44E-6 1.37E-3 view data
SRA701877 SRS3279689 Pancreatic islets 0 Alpha cells 4.97E-6 4.68E-4 view data
SRA701877 SRS3279690 Pancreatic islets 1 Alpha cells 1.46E-6 1.87E-4 view data
SRA701877 SRS3279691 Pancreatic islets 0 Alpha cells 2.82E-7 3.32E-5 view data
SRA701877 SRS3279691 Pancreatic islets 11 Alpha cells 8.66E-8 1.08E-5 view data
SRA701877 SRS3279691 Pancreatic islets 12 Alpha cells 1.53E-8 2.79E-6 view data
SRA701877 SRS3279692 Pancreatic islets 3 Alpha cells 1.10E-6 1.44E-4 view data
SRA701877 SRS3279693 Pancreatic islets 0 Alpha cells 3.25E-7 5.87E-5 view data
SRA701877 SRS3279693 Pancreatic islets 9 Alpha cells 1.10E-6 1.59E-4 view data
SRA701877 SRS3279693 Pancreatic islets 11 Alpha cells 3.21E-8 8.25E-6 view data
SRA701877 SRS3279694 Pancreatic islets 1 Alpha cells 4.48E-8 1.93E-5 view data
SRA701877 SRS3279694 Pancreatic islets 2 Alpha cells 2.13E-8 1.53E-5 view data
SRA701877 SRS3279695 Pancreatic islets 1 Alpha cells 3.75E-7 5.54E-5 view data
SRA585365 SRS2345685 Pancreas 4 Alpha cells 5.04E-20 3.88E-17 view data
SRA585365 SRS2345685 Pancreas 9 Alpha cells 1.06E-4 2.46E-2 view data
SRA585365 SRS2345686 Pancreas 6 Alpha cells 5.02E-17 8.50E-14 view data
SRA585365 SRS2345686 Pancreas 10 Alpha cells 4.49E-7 1.69E-4 view data
SRA585365 SRS2345687 Pancreas 7 Alpha cells 3.11E-19 3.59E-16 view data
SRA585365 SRS2345687 Pancreas 25 Alpha cells 3.57E-8 8.25E-6 view data
SRA585365 SRS2345688 Pancreas 9 Alpha cells 5.40E-17 7.07E-14 view data
SRA585365 SRS2345688 Pancreas 13 Alpha cells 2.80E-7 1.46E-4 view data
SRA585365 SRS3297649 Pancreas 8 Alpha cells 2.68E-16 5.16E-13 view data
SRA585365 SRS3297649 Pancreas 9 Alpha cells 3.74E-6 1.31E-3 view data
SRA585365 SRS3297650 Pancreas 5 Alpha cells 2.73E-18 4.06E-15 view data
SRA585365 SRS3297650 Pancreas 12 Alpha cells 6.49E-15 3.85E-12 view data
SRA585365 SRS3297650 Pancreas 17 Alpha cells 6.90E-15 3.85E-12 view data
SRA585365 SRS3297651 Pancreas 15 Alpha cells 6.53E-8 9.24E-6 view data
SRA585365 SRS3297652 Pancreas 14 Alpha cells 5.65E-8 8.41E-6 view data
SRA585365 SRS3297653 Pancreas 2 Alpha cells 4.04E-18 2.49E-15 view data
SRA585365 SRS3297653 Pancreas 4 Alpha cells 4.28E-20 7.91E-17 view data
SRA585365 SRS3297653 Pancreas 5 Alpha cells 3.44E-21 1.27E-17 view data
SRA585365 SRS3297653 Pancreas 10 Alpha cells 2.48E-10 4.83E-8 view data
SRA585365 SRS3297653 Pancreas 13 Alpha cells 1.45E-18 1.07E-15 view data
SRA585365 SRS3297653 Pancreas 16 Alpha cells 1.05E-13 3.22E-11 view data
SRA585365 SRS3297654 Pancreas 2 Alpha cells 4.04E-18 2.49E-15 view data
SRA585365 SRS3297654 Pancreas 4 Alpha cells 4.28E-20 7.91E-17 view data
SRA585365 SRS3297654 Pancreas 5 Alpha cells 3.44E-21 1.27E-17 view data
SRA585365 SRS3297654 Pancreas 10 Alpha cells 2.48E-10 4.83E-8 view data
SRA585365 SRS3297654 Pancreas 13 Alpha cells 1.45E-18 1.07E-15 view data
SRA585365 SRS3297654 Pancreas 16 Alpha cells 1.05E-13 3.22E-11 view data
SRA823298 SRS4144446 Alpha cells 0 Alpha cells 1.96E-4 1.29E-2 view data
SRA823298 SRS4144446 Alpha cells 1 Alpha cells 6.73E-8 1.68E-5 view data
SRA823298 SRS4144446 Alpha cells 2 Alpha cells 7.26E-8 1.68E-5 view data
SRA823298 SRS4144448 Alpha cells 0 Alpha cells 3.55E-4 2.55E-2 view data
SRA823298 SRS4144448 Alpha cells 1 Alpha cells 2.82E-4 2.17E-2 view data
SRA823298 SRS4144448 Alpha cells 2 Alpha cells 2.86E-7 1.54E-4 view data
SRA823298 SRS4144448 Alpha cells 3 Alpha cells 2.07E-7 1.54E-4 view data
SRA823298 SRS4144448 Alpha cells 4 Alpha cells 1.05E-5 2.27E-3 view data
SRA823298 SRS4144448 Alpha cells 5 Alpha cells 3.32E-5 3.98E-3 view data
SRA823298 SRS4144448 Alpha cells 6 Alpha cells 1.28E-6 3.45E-4 view data
SRA784304 SRS3823096 Pancreatic progenitor cells 0 Alpha cells 8.52E-18 1.57E-14 view data
SRA784304 SRS3823096 Pancreatic progenitor cells 3 Alpha cells 5.29E-14 1.22E-11 view data
SRA784304 SRS3823096 Pancreatic progenitor cells 7 Alpha cells 7.00E-15 3.24E-12 view data
SRA784304 SRS3823096 Pancreatic progenitor cells 8 Alpha cells 4.92E-5 4.33E-3 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 8 Alpha cells 8.77E-20 4.72E-17 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 12 Alpha cells 3.77E-16 5.42E-14 view data
SRA784304 SRS3823099 Pancreatic progenitor cells 5 Alpha cells 1.56E-11 4.00E-9 view data
SRA784304 SRS3823100 Pancreatic progenitor cells 0 Alpha cells 6.49E-7 1.30E-3 view data
SRA784304 SRS3823100 Pancreatic progenitor cells 2 Alpha cells 1.67E-4 4.77E-2 view data
SRA784304 SRS3823100 Pancreatic progenitor cells 3 Alpha cells 2.97E-5 1.19E-2 view data
SRA784304 SRS3823100 Pancreatic progenitor cells 5 Alpha cells 6.22E-6 3.11E-3 view data
SRA784304 SRS3823100 Pancreatic progenitor cells 7 Alpha cells 5.91E-6 3.11E-3 view data
SRA784304 SRS3823100 Pancreatic progenitor cells 12 Alpha cells 5.36E-6 3.11E-3 view data