Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Description: Langerhans cells are dendritic cells of the skin. LC are present in all layers of the epidermis and are most prominent in the stratum spinosum.

Gene expression markers for Langerhans cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
1
Mm Hs CD207 0.001 NA NA NA 0.001 2 Langerhans cells Mesoderm Skin Langerin,CLEC4K CD207 molecule Yflag
0
Mm Hs CLDN1 0.01 NA NA 0.029 0.006 5 Langerhans cells Mesoderm Skin SEMP1,ILVASC claudin 1 Yflag
0
Mm Hs ACHE 0.016 NA NA 0.005 0.02 6 Langerhans cells Mesoderm Skin YT acetylcholinesterase (Cartwright blood group) Yflag
0
Mm DEFB3 0 NA NA NA NA 1 Langerhans cells Mesoderm Skin defensin beta 3 flag
0
Mm Hs CCR6 0.001 NA NA NA 0.002 4 Langerhans cells Mesoderm Skin CKR-L3,GPR-CY4,CMKBR6,GPR29,DRY-6,DCR2,BN-1,CD196,STRL22 C-C motif chemokine receptor 6 flag
0
Hs FCGR2A 0.002 0.068 NA 0.009 NA 2 Langerhans cells Mesoderm Skin CD32A,IGFR2,CDw32,FCGR2A1 Fc fragment of IgG receptor IIa Yflag
0
Mm Hs TLR9 0 NA NA NA NA 7 Langerhans cells Mesoderm Skin CD289 toll like receptor 9 flag
0
Mm Hs TLR4 0 NA NA 0 NA 10 Langerhans cells Mesoderm Skin hToll,CD284,TLR-4,ARMD10 toll like receptor 4 Yflag
0
Mm Hs TLR2 0.014 NA NA 0.001 NA 8 Langerhans cells Mesoderm Skin TIL4,CD282 toll like receptor 2 Yflag
0
Mm Hs PTPRC 0.125 0.455 NA 0.213 0.106 8 Langerhans cells Mesoderm Skin T200,CD45 protein tyrosine phosphatase, receptor type C Yflag
0
Mm Hs CD80 0 NA NA NA 0 7 Langerhans cells Mesoderm Skin B7.1,B7-1,CD28LG,CD28LG1 CD80 molecule flag
0
Mm Hs EPCAM 0.117 NA NA 0.171 0.104 5 Langerhans cells Mesoderm Skin Ly74,TROP1,GA733-2,EGP34,EGP40,EGP-2,KSA,CD326,Ep-CAM,HEA125,KS1/4,MK-1,MH99,MOC31,323/A3,17-1A,TACST-1,CO-17A,M4S1,MIC18,TACSTD1 epithelial cell adhesion molecule Yflag
0
Mm Hs GPNMB 0.013 0.318 NA 0.026 0.009 4 Langerhans cells Mesoderm Skin NMB,HGFIN glycoprotein nmb flag
0
Mm Hs AHR 0.007 0.023 NA 0.011 0.007 8 Langerhans cells Mesoderm Skin bHLHe76 aryl hydrocarbon receptor flag
0
Mm Hs PRKCB 0.046 0.227 NA 0.027 0.049 2 Langerhans cells Mesoderm Skin PRKCB2,PKCB,PRKCB1 protein kinase C beta flag
0
Mm Hs EHF 0.024 NA NA 0.052 0.019 5 Langerhans cells Mesoderm Skin ESE3,ESEJ ETS homologous factor flag
0
Hs HLA-DRB9 0 NA NA NA NA 1 Langerhans cells Mesoderm Skin D6S206,D6S206E,HLA-DRB1L,HLA-DR1BL major histocompatibility complex, class II, DR beta 9 (pseudogene) flag
0
Hs HLA-DRB6 0.002 0.227 NA 0.011 NA 1 Langerhans cells Mesoderm Skin major histocompatibility complex, class II, DR beta 6 (pseudogene) flag
0
Hs HLA-DRB5 0.011 0.477 NA 0.057 NA 2 Langerhans cells Mesoderm Skin major histocompatibility complex, class II, DR beta 5 flag
0
Hs HLA-DRB1 0.033 1 NA 0.169 NA 2 Langerhans cells Mesoderm Skin HLA-DR1B major histocompatibility complex, class II, DR beta 1 Yflag
0
Hs HLA-DRA 0.039 1 NA 0.201 NA 4 Langerhans cells Mesoderm Skin HLA-DRA1 major histocompatibility complex, class II, DR alpha flag
0
Hs HLA-DQB3 0 NA NA NA NA 1 Langerhans cells Mesoderm Skin D6S205,D6S205E,DVB,DQB3,HLA-DVB major histocompatibility complex, class II, DQ beta 3 flag
0
Hs HLA-DQB2 0 0.023 NA 0.002 NA 1 Langerhans cells Mesoderm Skin HLA-DXB major histocompatibility complex, class II, DQ beta 2 flag
0
Hs HLA-DQB1 0.012 0.795 NA 0.055 NA 3 Langerhans cells Mesoderm Skin HLA-DQB major histocompatibility complex, class II, DQ beta 1 Yflag
0
Hs HLA-DQA2 0.003 0.136 NA 0.011 NA 1 Langerhans cells Mesoderm Skin HLA-DXA major histocompatibility complex, class II, DQ alpha 2 flag
0
Hs HLA-DQA1 0.01 0.773 NA 0.041 NA 3 Langerhans cells Mesoderm Skin HLA-DQA major histocompatibility complex, class II, DQ alpha 1 Yflag
0
Hs HLA-DMB 0.009 0.523 NA 0.037 NA 2 Langerhans cells Mesoderm Skin D6S221E,RING7 major histocompatibility complex, class II, DM beta flag
0
Hs HLA-DMA 0.022 0.909 NA 0.112 NA 2 Langerhans cells Mesoderm Skin D6S222E,RING6 major histocompatibility complex, class II, DM alpha flag
0
Hs FCGR1A 0.001 0.023 NA 0.003 NA 4 Langerhans cells Mesoderm Skin CD64,CD64A Fc fragment of IgG receptor Ia flag
0
Hs CD1A 0 NA NA NA NA 3 Langerhans cells Mesoderm Skin CD1a molecule flag

Datasets with computationally identified Langerhans cells

SRA SRS tissue cluster cell type p-value FDR View
SRA701877 SRS3279694 Pancreatic islets 11 Langerhans cells 7.83E-8 4.14E-5 view data
SRA779509 SRS3805267 Bone marrow 4 Langerhans cells 6.50E-5 1.07E-2 view data
SRA740174 SRS3548782 Bone marrow 6 Langerhans cells 1.67E-6 6.55E-4 view data
SRA782908 SRS3815607 Decidua 7 Langerhans cells 5.60E-7 1.98E-4 view data
SRA713577 SRS3363004 Peripheral blood mononuclear cells 5 Langerhans cells 6.05E-8 6.53E-6 view data
SRA716153 SRS3384792 CD34+ cord blood cells 3 Langerhans cells 1.17E-7 7.48E-5 view data
SRA716153 SRS3384792 CD34+ cord blood cells 10 Langerhans cells 1.49E-5 4.79E-3 view data
SRA661790 SRS2995083 Monocyte-derived macrophages 1 Langerhans cells 2.24E-4 2.48E-2 view data
SRA661790 SRS2995083 Monocyte-derived macrophages 3 Langerhans cells 4.79E-5 6.00E-3 view data
SRA661790 SRS2995083 Monocyte-derived macrophages 7 Langerhans cells 1.27E-6 2.38E-4 view data
SRA661790 SRS2995083 Monocyte-derived macrophages 8 Langerhans cells 1.93E-5 3.03E-3 view data
SRA661790 SRS2995083 Monocyte-derived macrophages 9 Langerhans cells 3.61E-7 8.48E-5 view data
SRA779509 SRS3805247 Bone marrow 15 Langerhans cells 6.15E-8 1.57E-5 view data
SRA779509 SRS3805268 Bone marrow 5 Langerhans cells 7.12E-8 9.91E-6 view data
SRA716153 SRS3384793 CD34+ cord blood cells 5 Langerhans cells 8.53E-6 1.07E-3 view data
SRA716153 SRS3384793 CD34+ cord blood cells 6 Langerhans cells 2.89E-5 3.31E-3 view data
SRA742961 SRS3565209 Prostate 10 Langerhans cells 9.71E-5 2.45E-2 view data
SRA878024 SRS4660847 Lungs 1 Langerhans cells 1.60E-6 1.27E-3 view data
SRA550660 SRS2089637 Peripheral blood mononuclear cells 13 Langerhans cells 1.08E-5 2.49E-3 view data
SRA878024 SRS4660848 Lungs 2 Langerhans cells 2.58E-5 2.41E-3 view data
SRA661790 SRS2995082 Monocyte-derived macrophages 0 Langerhans cells 1.36E-4 3.60E-2 view data
SRA661790 SRS2995082 Monocyte-derived macrophages 9 Langerhans cells 2.61E-5 1.37E-2 view data
SRA740174 SRS3548783 Bone marrow 7 Langerhans cells 4.04E-5 1.73E-2 view data
SRA779509 SRS3805264 Bone marrow 2 Langerhans cells 8.83E-5 9.79E-3 view data
SRA740174 SRS3548780 Bone marrow 6 Langerhans cells 1.18E-5 5.66E-3 view data
SRA661790 SRS2995084 Monocyte-derived macrophages 0 Langerhans cells 8.39E-6 1.32E-3 view data
SRA661790 SRS2995084 Monocyte-derived macrophages 1 Langerhans cells 1.54E-6 4.44E-4 view data
SRA661790 SRS2995084 Monocyte-derived macrophages 3 Langerhans cells 1.98E-8 1.71E-5 view data
SRA661790 SRS2995084 Monocyte-derived macrophages 4 Langerhans cells 6.29E-8 3.63E-5 view data
SRA661790 SRS2995084 Monocyte-derived macrophages 5 Langerhans cells 8.40E-6 1.32E-3 view data
SRA661790 SRS2995084 Monocyte-derived macrophages 6 Langerhans cells 1.44E-5 1.92E-3 view data
SRA661790 SRS2995084 Monocyte-derived macrophages 8 Langerhans cells 7.88E-6 1.32E-3 view data
SRA661790 SRS2995084 Monocyte-derived macrophages 9 Langerhans cells 3.36E-9 5.81E-6 view data
SRA779509 SRS3805269 Bone marrow 19 Langerhans cells 1.02E-7 1.22E-5 view data
SRA779509 SRS3805246 Bone marrow 10 Langerhans cells 1.64E-4 2.07E-2 view data
SRA779509 SRS3805246 Bone marrow 19 Langerhans cells 3.26E-8 1.02E-5 view data
SRA779509 SRS3805257 Bone marrow 16 Langerhans cells 1.50E-8 2.73E-6 view data
SRA716153 SRS3384795 CD34+ cord blood cells 4 Langerhans cells 2.97E-5 9.20E-3 view data
SRA716153 SRS3384795 CD34+ cord blood cells 12 Langerhans cells 3.52E-8 4.36E-5 view data
SRA617020 SRS2566664 B cells 0 Langerhans cells 5.84E-5 4.11E-3 view data
SRA740174 SRS3548781 Bone marrow 6 Langerhans cells 1.01E-5 4.01E-3 view data
SRA779509 SRS3805265 Bone marrow 12 Langerhans cells 9.18E-10 1.72E-7 view data
SRA721637 SRS3416995 Lymph node 0 Langerhans cells 5.95E-10 1.35E-7 view data
SRA719952 SRS3407249 NK cells 18 Langerhans cells 2.11E-4 7.32E-3 view data
SRA636225 SRS2737287 Circulating tumor cells in hepatocellular carcinoma 3 Langerhans cells 2.86E-7 6.63E-5 view data
SRA636225 SRS2737287 Circulating tumor cells in hepatocellular carcinoma 6 Langerhans cells 9.32E-8 2.36E-5 view data
SRA701877 SRS3279693 Pancreatic islets 13 Langerhans cells 1.47E-6 3.03E-4 view data