Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Description: Resident macrophages located in the liver. Important for normal physiology and homeostasis as well as participating in the acute and chronic responses of the liver to toxic compounds.
Synonym(s): stellate macrophages, Kupffer-Browicz cells

Gene expression markers for Kupffer cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
8
Mm Hs C1QA 0.07 0 1 0.024 0.08 1 Kupffer cells Mesoderm Liver complement C1q A chain Yflag
4
Mm Hs CSF1R 0.064 0 0.969 0.018 0.074 4 Kupffer cells Mesoderm Liver C-FMS,CSFR,CD115,FMS colony stimulating factor 1 receptor Yflag
2
Mm Hs CLEC4F 0.003 0 0.969 0 0.002 1 Kupffer cells Mesoderm Liver FLJ39110,KCLR C-type lectin domain family 4 member F flag
2
Mm Hs CD163 0.005 0 0.5 0.007 0.003 4 Kupffer cells Mesoderm Liver MM130,SCARI1 CD163 molecule flag
1
Mm Hs TIMD4 0.006 0 0 0.024 0 1 Kupffer cells Mesoderm Liver T cell immunoglobulin and mucin domain containing 4 flag
1
Mm Hs VSIG4 0.005 0 0 0.013 0 3 Kupffer cells Mesoderm Liver Z39IG V-set and immunoglobulin domain containing 4 flag
1
Mm Hs CLEC1B 0.003 0 0.75 0.001 0.002 3 Kupffer cells Mesoderm Liver CLEC2 C-type lectin domain family 1 member B flag
0
Mm Hs GPIHBP1 0.017 0 0.094 0.005 0.019 4 Kupffer cells Mesoderm Liver LOC338328,GPI-HBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Yflag
0
Mm Hs SLC15A3 0.016 0 0 0.008 0 2 Kupffer cells Mesoderm Liver PHT2,hPTR3 solute carrier family 15 member 3 flag
0
Mm Hs MARCO 0.003 0 0.438 0.004 0.002 2 Kupffer cells Mesoderm Liver SCARA2,SR-A6 macrophage receptor with collagenous structure flag
0
Mm EAR2 0.009 0 0.438 0 0.01 5 Kupffer cells Mesoderm Liver eosinophil-associated, ribonuclease A family, member 2 flag
0
Mm Hs HFE 0.017 0 0.5 0 0.02 5 Kupffer cells Mesoderm Liver HLA-H homeostatic iron regulator Yflag
0
Mm Hs CD38 0.016 0 0.563 0.014 0.015 6 Kupffer cells Mesoderm Liver CD38 molecule flag
0
Mm ADGRE4 0.004 0 0.594 0 0.004 3 Kupffer cells Mesoderm Liver adhesion G protein-coupled receptor E4 flag
0
Mm Hs CCR5 0.015 0 0.625 0 0.017 6 Kupffer cells Mesoderm Liver CKR-5,CC-CKR-5,CKR5,CD195,IDDM22,CMKBR5 C-C motif chemokine receptor 5 (gene/pseudogene) Yflag
0
Mm Hs CLEC4E 0.006 0 0 0.003 0.006 2 Kupffer cells Mesoderm Liver mincle,CLECSF9 C-type lectin domain family 4 member E flag
0
Mm Hs FOLR2 0.001 0 0.031 0.004 0 1 Kupffer cells Mesoderm Liver folate receptor beta flag
0
Mm Hs PLTP 0.009 0 0.031 0.026 0.005 3 Kupffer cells Mesoderm Liver BPIFE phospholipid transfer protein flag
0
Hs FTL 0.178 0 0 0.939 0 2 Kupffer cells Mesoderm Liver MGC71996,NBIA3 ferritin light chain Yflag
0
Mm Hs IRF7 0.033 0 0.781 0.029 0.031 4 Kupffer cells Mesoderm Liver interferon regulatory factor 7 Yflag
0
Mm Hs SPIC 0.002 0 0 0 0 2 Kupffer cells Mesoderm Liver MGC40611,SPI-C Spi-C transcription factor flag
0
Mm Hs C1QC 0.066 0 1 0.017 0.077 1 Kupffer cells Mesoderm Liver C1QG complement C1q C chain Yflag
0
Mm Hs C1QB 0.071 0 1 0.019 0.081 2 Kupffer cells Mesoderm Liver complement C1q B chain Yflag
0
Mm Hs TNF 0.008 0 0 0.001 0 6 Kupffer cells Mesoderm Liver TNFSF2,DIF,TNF-alpha,TNFA tumor necrosis factor Yflag
0
Mm Hs VDR 0.011 0 0 0.003 0 8 Kupffer cells Mesoderm Liver NR1I1,PPP1R163 vitamin D receptor Yflag
0
Mm Hs TLR9 0 0 0 0 0 7 Kupffer cells Mesoderm Liver CD289 toll like receptor 9 flag
0
Mm Hs PPARA 0.001 0 0 0.003 0.001 3 Kupffer cells Mesoderm Liver hPPAR,NR1C1,PPAR peroxisome proliferator activated receptor alpha flag
0
Mm Hs MSR1 0.012 0 0.625 0.011 0.011 1 Kupffer cells Mesoderm Liver SCARA1,CD204,SR-AI,SR-AII,SR-AIII,SR-A macrophage scavenger receptor 1 Yflag
0
Mm Hs STARD5 0.006 0 0 0 0 1 Kupffer cells Mesoderm Liver MGC10327 StAR related lipid transfer domain containing 5 flag
0
Mm Hs TLR4 0 0 0 0 0 10 Kupffer cells Mesoderm Liver hToll,CD284,TLR-4,ARMD10 toll like receptor 4 Yflag
0
Mm Hs MMP13 0.003 0 0 0 0.003 3 Kupffer cells Mesoderm Liver CLG3 matrix metallopeptidase 13 Yflag
0
Mm Hs PROK2 0.003 0 0 0.004 0.002 2 Kupffer cells Mesoderm Liver PK2,BV8,MIT1,KAL4 prokineticin 2 Yflag
0
Mm FCNA 0.007 0 0.969 0 0.006 2 Kupffer cells Mesoderm Liver ficolin A flag
0
Mm Hs CD14 0.051 0 0.25 0.027 0.055 6 Kupffer cells Mesoderm Liver CD14 molecule flag
0
Mm Hs CHIT1 0.003 0 0 0.001 0.004 2 Kupffer cells Mesoderm Liver CHIT,CHI3 chitinase 1 Yflag
0
Mm Hs OSM 0.007 0 0 0 0.008 2 Kupffer cells Mesoderm Liver MGC20461 oncostatin M flag
0
Mm Hs PPARD 0.009 0 0 0.002 0.01 3 Kupffer cells Mesoderm Liver NUC1,NUCII,FAAR,NR1C2 peroxisome proliferator activated receptor delta flag
0
Mm Hs ADGRE1 0.033 0 0.969 0.001 0.039 6 Kupffer cells Mesoderm Liver TM7LN3,EMR1 adhesion G protein-coupled receptor E1 flag
0
Mm Hs IL1B 0.027 0 0.219 0.025 0.027 6 Kupffer cells Mesoderm Liver IL1F2,IL-1B,IL1-BETA interleukin 1 beta Yflag
0
Mm Hs SLC40A1 0.033 0 0 0.035 0 3 Kupffer cells Mesoderm Liver MTP1,IREG1,FPN1,HFE4,SLC11A3 solute carrier family 40 member 1 Yflag
0
Mm Hs MPO 0.023 0 0 0.021 0.023 2 Kupffer cells Mesoderm Liver myeloperoxidase Yflag
0
Hs G6PD 0.011 0 0 0.047 0 1 Kupffer cells Mesoderm Liver G6PD1 glucose-6-phosphate dehydrogenase Yflag
0
Hs LYZ 0.008 0 0 0.041 0 6 Kupffer cells Mesoderm Liver lysozyme Yflag
-1
Mm SIGLECF 0.002 NA NA NA NA 5 Kupffer cells Mesoderm Liver sialic acid binding Ig-like lectin F flag
-1
Mm Hs SLC11A1 0.017 0 0 0.007 0 5 Kupffer cells Mesoderm Liver NRAMP,NRAMP1 solute carrier family 11 member 1 Yflag
-1
Mm Hs CLEC4G 0.001 0 0.094 0 0.001 3 Kupffer cells Mesoderm Liver UNQ431,LSECtin C-type lectin domain family 4 member G flag
-1
Mm Hs DNASE1L3 0.015 0 0.531 0.01 0.015 4 Kupffer cells Mesoderm Liver DNAS1L3,LSD deoxyribonuclease 1 like 3 Yflag
-1
Mm Hs MNDA 0.019 0 0.188 0.046 0.013 3 Kupffer cells Mesoderm Liver PYHIN3 myeloid cell nuclear differentiation antigen flag
-2
Mm Hs TREM1 0.003 0 0 0.001 0 2 Kupffer cells Mesoderm Liver TREM-1,CD354 triggering receptor expressed on myeloid cells 1 flag

Datasets with computationally identified Kupffer cells

SRA SRS tissue cluster cell type p-value FDR View
SRA739096 SRS3545823 Liver 0 Kupffer cells 2.30E-15 7.97E-13 view data
SRA739096 SRS3545823 Liver 2 Kupffer cells 1.13E-13 2.27E-11 view data
SRA739096 SRS3545823 Liver 3 Kupffer cells 1.44E-10 2.18E-8 view data
SRA739096 SRS3545823 Liver 4 Kupffer cells 2.14E-15 7.97E-13 view data
SRA739096 SRS3545823 Liver 6 Kupffer cells 1.17E-9 1.41E-7 view data
SRA739096 SRS3545823 Liver 8 Kupffer cells 1.68E-15 7.97E-13 view data
SRA739096 SRS3545823 Liver 9 Kupffer cells 1.84E-16 1.49E-13 view data
SRA739096 SRS3545823 Liver 11 Kupffer cells 5.18E-15 1.57E-12 view data
SRA739096 SRS3545823 Liver 13 Kupffer cells 4.68E-5 2.70E-3 view data
SRA653146 SRS3044244 Liver 8 Kupffer cells 5.34E-12 6.25E-10 view data
SRA753635 SRS3630214 Uterus 12 Kupffer cells 2.39E-4 3.25E-2 view data
SRA739096 SRS3545825 Liver 4 Kupffer cells 4.68E-7 4.60E-5 view data
SRA739096 SRS3545825 Liver 6 Kupffer cells 3.45E-13 9.07E-11 view data
SRA739096 SRS3545825 Liver 8 Kupffer cells 7.73E-6 5.80E-4 view data
SRA739096 SRS3545825 Liver 10 Kupffer cells 3.16E-5 1.95E-3 view data
SRA739096 SRS3545825 Liver 13 Kupffer cells 7.95E-15 2.78E-12 view data
SRA739096 SRS3545825 Liver 15 Kupffer cells 6.72E-6 5.29E-4 view data
SRA739096 SRS3545825 Liver 17 Kupffer cells 9.15E-5 5.06E-3 view data
SRA638923 SRS2797074 Liver 2 Kupffer cells 2.25E-7 4.74E-5 view data
SRA739096 SRS3545822 Liver 0 Kupffer cells 4.90E-12 7.73E-10 view data
SRA739096 SRS3545822 Liver 1 Kupffer cells 9.73E-18 9.98E-15 view data
SRA739096 SRS3545822 Liver 2 Kupffer cells 1.72E-15 5.88E-13 view data
SRA739096 SRS3545822 Liver 3 Kupffer cells 1.60E-12 2.98E-10 view data
SRA739096 SRS3545822 Liver 4 Kupffer cells 4.16E-7 3.42E-5 view data
SRA739096 SRS3545822 Liver 5 Kupffer cells 3.10E-13 6.36E-11 view data
SRA739096 SRS3545822 Liver 6 Kupffer cells 9.18E-17 3.77E-14 view data
SRA739096 SRS3545822 Liver 7 Kupffer cells 3.41E-17 1.75E-14 view data
SRA739096 SRS3545822 Liver 8 Kupffer cells 9.61E-15 2.82E-12 view data
SRA739096 SRS3545822 Liver 10 Kupffer cells 5.32E-14 1.36E-11 view data
SRA739096 SRS3545822 Liver 11 Kupffer cells 1.16E-13 2.64E-11 view data
SRA653146 SRS2874275 Liver 2 Kupffer cells 1.13E-15 1.88E-13 view data
SRA638923 SRS2960038 Pancreas 8 Kupffer cells 1.03E-7 3.57E-5 view data