Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Description: Müller cells are glia cells found in the retina. They are the most common type of glial cell found in the retina. While their cell bodies are located in the inner nuclear layer of the retina, they span across the entire retina. The major role of the Müller cells is to maintain the structural and functional stability of retinal cells.

Gene expression markers for Müller cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
1
Mm Hs AQP4 0.024 0 0.842 0.006 0.028 9 Müller cells Ectoderm Eye MIWC aquaporin 4 flag
0
Mm Hs GPR37 0.034 0 0.737 0.005 0.04 2 Müller cells Ectoderm Eye EDNRBL,hET(B)R-LP,PAELR G protein-coupled receptor 37 flag
0
Mm Hs COL5A1 0.028 0 0 0.036 0.025 2 Müller cells Ectoderm Eye collagen type V alpha 1 chain Yflag
0
Mm Hs COL6A1 0.063 0 0 0.09 0.056 3 Müller cells Ectoderm Eye collagen type VI alpha 1 chain Yflag
0
Mm Hs TLR2 0.014 0 0 0.001 0 8 Müller cells Ectoderm Eye TIL4,CD282 toll like receptor 2 Yflag
0
Mm Hs GLUL 0.298 0 1 0.3 0.304 3 Müller cells Ectoderm Eye GLNS glutamate-ammonia ligase Yflag
0
Mm Hs CLU 0.168 0 0.947 0.216 0.162 2 Müller cells Ectoderm Eye SGP-2,SP-40,TRPM-2,KUB1,CLU2,CLI,APOJ clusterin flag
0
Mm Hs S100A16 0.192 0 0 0.179 0 1 Müller cells Ectoderm Eye S100F,DT1P1A7,MGC17528 S100 calcium binding protein A16 flag
0
Mm Hs SOX2 0.082 0 0 0.029 0 6 Müller cells Ectoderm Eye SRY-box 2 Yflag
0
Mm Hs APOE 0.343 0 1 0.133 0.389 4 Müller cells Ectoderm Eye AD2 apolipoprotein E Yflag
0
Mm Hs DBI 0.597 0 0.947 0.468 0.621 1 Müller cells Ectoderm Eye ACBD1 diazepam binding inhibitor, acyl-CoA binding protein flag
0
Mm Hs GNAI2 0.46 0 1 0.186 0.52 1 Müller cells Ectoderm Eye GNAI2B G protein subunit alpha i2 Yflag
0
Mm Hs COL11A1 0.009 0 0.105 0.01 0.009 3 Müller cells Ectoderm Eye STL2,CO11A1,COLL6 collagen type XI alpha 1 chain Yflag
0
Mm Hs PRDX6 0.396 0 0.947 0.474 0.37 2 Müller cells Ectoderm Eye AOP2,KIAA0106,1-Cys,NSGPx,PRX,aiPLA2,MGC46173 peroxiredoxin 6 flag
0
Mm Hs SLC1A3 0.074 0 0 0.011 0 6 Müller cells Ectoderm Eye EAAT1,GLAST,EA6 solute carrier family 1 member 3 Yflag
0
Mm Hs HES1 0.129 0 0.947 0.146 0.127 4 Müller cells Ectoderm Eye FLJ20408,HES-1,Hes1,bHLHb39,HRY hes family bHLH transcription factor 1 flag
0
Mm Hs KIT 0.015 0 0 0.003 0.019 10 Müller cells Ectoderm Eye CD117,SCFR,C-Kit,PBT KIT proto-oncogene receptor tyrosine kinase Yflag
0
Mm Hs CRB1 0 0 0 0 0 1 Müller cells Ectoderm Eye LCA8,RP12 crumbs 1, cell polarity complex component Yflag
0
Mm Hs ANXA4 0.06 0 0 0.074 0.057 2 Müller cells Ectoderm Eye ANX4 annexin A4 flag
0
Mm Hs CD44 0.127 0 0 0.3 0.088 9 Müller cells Ectoderm Eye IN,MC56,Pgp1,CD44R,HCELL,CSPG8,MIC4,MDU2,MDU3 CD44 molecule (Indian blood group) Yflag
0
Mm GSTT1 0.022 0 0 0 0.028 4 Müller cells Ectoderm Eye glutathione S-transferase theta 1 flag
0
Mm Hs GSTM5 0.201 0 0.105 0.005 0.25 2 Müller cells Ectoderm Eye glutathione S-transferase mu 5 flag
0
Mm Hs SLC6A1 0.043 0 0 0.003 0 3 Müller cells Ectoderm Eye GAT1,GABATR,GABATHG solute carrier family 6 member 1 Yflag
0
Mm Hs SFTPA1 0.015 0 0 0.018 0 3 Müller cells Ectoderm Eye SP-A,SP-A1,COLEC4,SFTP1 surfactant protein A1 Yflag
0
Mm Hs COL3A1 0.086 0 0 0.099 0.081 4 Müller cells Ectoderm Eye EDS4A collagen type III alpha 1 chain Yflag
0
Mm Hs IL6 0.007 0 0 0.013 0.006 6 Müller cells Ectoderm Eye IL-6,BSF2,HSF,IFNB2 interleukin 6 Yflag
0
Mm Hs CNR2 0 0 0 0 0 2 Müller cells Ectoderm Eye CB2 cannabinoid receptor 2 flag
0
Mm Hs VEGFA 0.021 0 0 0.025 0 10 Müller cells Ectoderm Eye VEGF-A,VPF,VEGF vascular endothelial growth factor A Yflag
0
Mm Hs SLC38A5 0.02 0 0 0.023 0 3 Müller cells Ectoderm Eye SN2,JM24 solute carrier family 38 member 5 flag
0
Mm Hs SLC38A3 0.018 0 0 0.001 0 2 Müller cells Ectoderm Eye SN1 solute carrier family 38 member 3 flag
0
Mm Hs IL33 0.018 0 0.579 0.011 0.02 6 Müller cells Ectoderm Eye DVS27,DKFZp586H0523,NF-HEV,IL1F11,C9orf26 interleukin 33 flag
0
Mm Hs RDH10 0.012 0 0 0.018 0 1 Müller cells Ectoderm Eye SDR16C4 retinol dehydrogenase 10 flag
0
Mm Hs SLITRK2 0.006 0 0 0.002 0 2 Müller cells Ectoderm Eye KIAA1854,SLITL1,TMEM257,CXorf1 SLIT and NTRK like family member 2 flag
0
Mm Hs SYNPR 0.022 0 0 0.001 0 5 Müller cells Ectoderm Eye MGC26651 synaptoporin flag
0
Mm ABCA8A 0.01 0 0.684 0 0.011 1 Müller cells Ectoderm Eye ATP-binding cassette, sub-family A (ABC1), member 8a flag
0
Mm Hs CROT 0.009 0 0.684 0.005 0.01 1 Müller cells Ectoderm Eye carnitine O-octanoyltransferase flag
0
Mm Hs COL9A1 0.006 0 1 0.007 0.005 2 Müller cells Ectoderm Eye collagen type IX alpha 1 chain Yflag
0
Mm Hs COL4A2 0.094 0 0 0.081 0.096 1 Müller cells Ectoderm Eye FLJ22259,DKFZp686I14213 collagen type IV alpha 2 chain Yflag
0
Mm Hs COL2A1 0.009 0 0.474 0.012 0.006 2 Müller cells Ectoderm Eye STL1,SEDC,AOM collagen type II alpha 1 chain Yflag
0
Mm Hs COL1A1 0.081 0 0 0.1 0.073 6 Müller cells Ectoderm Eye collagen type I alpha 1 chain Yflag
0
Mm Hs VSX2 0.004 0 0 0 0 4 Müller cells Ectoderm Eye RET1,HOX10,CHX10 visual system homeobox 2 Yflag
0
Mm Hs DKK3 0.034 0 1 0.038 0.034 6 Müller cells Ectoderm Eye REIC dickkopf WNT signaling pathway inhibitor 3 flag
0
Mm Hs RLBP1 0.028 0 0 0 0 2 Müller cells Ectoderm Eye CRALBP retinaldehyde binding protein 1 Yflag
0
Mm Hs DAPL1 0.009 0 1 0.008 0.008 1 Müller cells Ectoderm Eye death associated protein like 1 flag
0
Mm Hs SIX3OS1 0.005 NA NA NA NA 1 Müller cells Ectoderm Eye SIX homeobox 3, opposite strand 1 flag
0
Mm CAR14 0.002 0 0.789 0 0.002 1 Müller cells Ectoderm Eye carbonic anhydrase 14 flag
0
Mm Hs CRYM 0.015 0 0.737 0.002 0.018 2 Müller cells Ectoderm Eye DFNA40 crystallin mu Yflag
-1
Mm Hs KCNJ2 0.002 0 0 0.01 0 1 Müller cells Ectoderm Eye Kir2.1,IRK1,LQT7 potassium voltage-gated channel subfamily J member 2 Yflag
-1
Mm Hs ZBED4 0 0 0 0.001 0 2 Müller cells Ectoderm Eye KIAA0637 zinc finger BED-type containing 4 flag
-1
Hs CA2 0.011 0 0 0.065 0 3 Müller cells Ectoderm Eye Car2,CA-II,CAII carbonic anhydrase 2 Yflag
-1
Mm Hs ATG4B 0.025 0 0 0.039 0.021 1 Müller cells Ectoderm Eye Apg4B,KIAA0943,DKFZp586D1822,APG4B autophagy related 4B cysteine peptidase flag
-1
Mm Hs ITM2B 0.854 0 1 0.736 0.891 1 Müller cells Ectoderm Eye BRI,E25B,E3-16,BRICD2B,BRI2 integral membrane protein 2B Yflag
-1
Mm Hs SPC25 0.062 0 0 0.022 0 1 Müller cells Ectoderm Eye MGC22228,AD024,SPBC25 SPC25, NDC80 kinetochore complex component flag
-1
Mm Hs KCNJ10 0.046 0 0.105 0.002 0.057 2 Müller cells Ectoderm Eye Kir4.1,Kir1.2 potassium voltage-gated channel subfamily J member 10 Yflag

Datasets with computationally identified Müller cells

SRA SRS tissue cluster cell type p-value FDR View
SRA716152 SRS3384791 Retinal ganglion cells 28 Müller cells 4.74E-6 1.54E-4 view data
SRA203368 SRS866908 Retina 8 Müller cells 2.12E-25 1.40E-22 view data
SRA203368 SRS866906 Retina 7 Müller cells 1.19E-21 8.02E-19 view data
SRA429320 SRS1467254 Retina 2 Müller cells 6.67E-27 2.66E-24 view data
SRA203368 SRS866910 Retina 5 Müller cells 1.70E-20 8.06E-18 view data
SRA203368 SRS866910 Retina 15 Müller cells 6.11E-5 6.96E-3 view data
SRA203368 SRS866911 Retina 3 Müller cells 5.00E-23 4.15E-20 view data
SRA203368 SRS866911 Retina 22 Müller cells 1.25E-7 1.64E-5 view data
SRA429320 SRS1467253 Retina 1 Müller cells 1.48E-29 9.37E-27 view data
SRA203368 SRS866909 Retina 5 Müller cells 1.39E-30 1.13E-27 view data
SRA203368 SRS866907 Retina 7 Müller cells 3.10E-27 3.02E-24 view data
SRA203368 SRS866912 Retina 6 Müller cells 2.33E-29 2.23E-26 view data
SRA203368 SRS866912 Retina 26 Müller cells 2.98E-8 3.95E-6 view data
SRA429320 SRS1467250 Retina 2 Müller cells 2.65E-25 9.10E-23 view data
SRA429320 SRS1467250 Retina 13 Müller cells 1.46E-6 2.52E-4 view data
SRA429320 SRS1467249 Retina 1 Müller cells 3.01E-25 9.37E-23 view data
SRA429320 SRS1467251 Retina 2 Müller cells 4.47E-26 1.99E-23 view data
SRA429320 SRS1467251 Retina 12 Müller cells 5.26E-5 6.88E-3 view data
SRA429320 SRS1467252 Retina 1 Müller cells 5.68E-28 2.70E-25 view data