Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Description: Plasmacytoid dendritic cells are a rare type of immune cell that are known to secrete large quantities of type 1 interferon (IFNs) in response to a viral infection. They circulate in the blood and are found in peripheral lymphoid organs. They develop from bone marrow hematopoietic stem cells and constitute < 0.4% of peripheral blood mononuclear cells (PBMC). Other than conducting antiviral mechanisms, pDCs are considered to be key in linking the innate and adaptive immune systems.

Gene expression markers for Plasmacytoid dendritic cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
5
Mm Hs BST2 0.177 0.455 1 0.203 0.166 1 Plasmacytoid dendritic cells Mesoderm Immune system CD317,tetherin bone marrow stromal cell antigen 2 flag
1
Mm Hs MAP3K2 0.009 0.227 0 0.021 0.006 1 Plasmacytoid dendritic cells Mesoderm Immune system MEKK2B,MEKK2 mitogen-activated protein kinase kinase kinase 2 flag
1
Mm Hs KLK1 0.013 0 1 0.008 0.013 7 Plasmacytoid dendritic cells Mesoderm Immune system Klk6 kallikrein 1 Yflag
1
Mm CMAH 0.003 0 0.3 0 0.004 2 Plasmacytoid dendritic cells Mesoderm Immune system cytidine monophospho-N-acetylneuraminic acid hydroxylase flag
1
Mm Hs TRADD 0.015 0.045 0 0.027 0 1 Plasmacytoid dendritic cells Mesoderm Immune system Hs.89862 TNFRSF1A associated via death domain flag
1
Hs CLEC4C 0.001 0.409 0 0 0 1 Plasmacytoid dendritic cells Mesoderm Immune system HECL,DLEC,BDCA2,CD303,CLECSF11,CLECSF7 C-type lectin domain family 4 member C flag
1
Hs LILRA4 0.001 1 0 0.002 0 1 Plasmacytoid dendritic cells Mesoderm Immune system ILT7,CD85g leukocyte immunoglobulin like receptor A4 flag
1
Mm Hs NRP1 0.099 0.5 0.05 0.062 0.107 1 Plasmacytoid dendritic cells Mesoderm Immune system VEGF165R,CD304 neuropilin 1 flag
0
Mm Hs S100A8 0.064 0.273 0 0.079 0 12 Plasmacytoid dendritic cells Mesoderm Immune system P8,CGLA,CAGA S100 calcium binding protein A8 flag
0
Mm Hs CUX2 0.024 0 0 0 0.03 3 Plasmacytoid dendritic cells Mesoderm Immune system KIAA0293,CDP2,CUTL2 cut like homeobox 2 flag
0
Mm ZFP521 0.001 NA NA NA NA 2 Plasmacytoid dendritic cells Mesoderm Immune system zinc finger protein 521 flag
0
Mm Hs MCTP2 0.001 0 0.05 0 0.001 1 Plasmacytoid dendritic cells Mesoderm Immune system FLJ11175,FLJ33303 multiple C2 and transmembrane domain containing 2 flag
0
Mm Hs IRF5 0.028 0 0.8 0 0.033 2 Plasmacytoid dendritic cells Mesoderm Immune system interferon regulatory factor 5 Yflag
0
Mm Hs CCR9 0.005 0 1 0 0.004 1 Plasmacytoid dendritic cells Mesoderm Immune system GPR-9-6,CDw199,GPR28 C-C motif chemokine receptor 9 flag
0
Mm Hs BLNK 0.017 0 1 0.001 0.018 2 Plasmacytoid dendritic cells Mesoderm Immune system SLP65,Ly57,SLP-65,BLNK-s,BASH,bca B cell linker Yflag
0
Mm Hs GRM8 0.002 0 0.05 0.004 0.001 2 Plasmacytoid dendritic cells Mesoderm Immune system GLUR8,GPRC1H,mGlu8,MGLUR8 glutamate metabotropic receptor 8 flag
0
Mm Hs PRKCA 0.033 0 1 0.015 0.036 5 Plasmacytoid dendritic cells Mesoderm Immune system PKCA protein kinase C alpha flag
0
Mm Hs CDH1 0.056 0 0 0.042 0.057 15 Plasmacytoid dendritic cells Mesoderm Immune system uvomorulin,CD324,UVO cadherin 1 Yflag
0
Mm KLRA17 0.002 0 1 0 0.001 1 Plasmacytoid dendritic cells Mesoderm Immune system killer cell lectin-like receptor, subfamily A, member 17 flag
0
Mm Hs IL17RB 0.001 0 0 0 0.001 4 Plasmacytoid dendritic cells Mesoderm Immune system IL17RH1,EVI27,CRL4,IL17BR interleukin 17 receptor B flag
0
Mm Hs CARD6 0 0 0 0 0 1 Plasmacytoid dendritic cells Mesoderm Immune system CINCIN1 caspase recruitment domain family member 6 flag
0
Mm Hs JCHAIN 0.017 1 0 0.043 0.008 3 Plasmacytoid dendritic cells Mesoderm Immune system IGCJ,JCH,IGJ joining chain of multimeric IgA and IgM flag
0
Mm Hs SERPINF1 0.057 1 0 0.1 0 3 Plasmacytoid dendritic cells Mesoderm Immune system EPC-1,PIG35,PEDF serpin family F member 1 Yflag
0
Mm Hs IRF8 0.069 1 1 0.021 0.074 4 Plasmacytoid dendritic cells Mesoderm Immune system IRF-8,ICSBP,ICSBP1 interferon regulatory factor 8 Yflag
0
Mm Hs ITM2C 0.354 1 1 0.224 0.381 1 Plasmacytoid dendritic cells Mesoderm Immune system BRI3,E25,hRPC.1050_D_4,ITM3,BRICD2C integral membrane protein 2C flag
0
Mm Hs TCF4 0.394 0.909 0 0.164 0 3 Plasmacytoid dendritic cells Mesoderm Immune system SEF2-1B,ITF2,bHLHb19,E2-2 transcription factor 4 Yflag
0
Mm Hs BCL11A 0.134 0.909 1 0.108 0.142 4 Plasmacytoid dendritic cells Mesoderm Immune system BCL11A-XL,BCL11A-L,BCL11A-S,CTIP1,HBFQTL5,ZNF856,EVI9 B cell CLL/lymphoma 11A Yflag
0
Mm Hs SLC15A4 0.006 0.455 0 0.016 0 1 Plasmacytoid dendritic cells Mesoderm Immune system PHT1,PTR4 solute carrier family 15 member 4 flag
0
Mm Hs MZB1 0.025 0.955 0.4 0.032 0.02 3 Plasmacytoid dendritic cells Mesoderm Immune system MGC29506,HSPC190,pERp1,MEDA-7 marginal zone B and B1 cell specific protein flag
0
Mm Hs DERL3 0.01 0.773 0 0.029 0.004 2 Plasmacytoid dendritic cells Mesoderm Immune system FLJ43842,MGC71803,derlin-3,IZP6,C22orf14 derlin 3 flag
0
Mm Hs ZFAT 0.001 0 0 0.001 0 1 Plasmacytoid dendritic cells Mesoderm Immune system KIAA1485,ZNF406,ZFAT1 zinc finger and AT-hook domain containing Yflag
0
Mm Hs ERN1 0.002 0.091 0 0.005 0.001 2 Plasmacytoid dendritic cells Mesoderm Immune system IRE1,IRE1P endoplasmic reticulum to nucleus signaling 1 flag
0
Mm Hs CD8A 0.01 0 0 0.016 0.009 6 Plasmacytoid dendritic cells Mesoderm Immune system CD8 CD8a molecule Yflag
0
Mm Hs CD40 0.012 0 0 0.013 0.011 10 Plasmacytoid dendritic cells Mesoderm Immune system Bp50,TNFRSF5 CD40 molecule Yflag
0
Mm Hs CD80 0 0 0 0 0 7 Plasmacytoid dendritic cells Mesoderm Immune system B7.1,B7-1,CD28LG,CD28LG1 CD80 molecule flag
0
Mm Hs CD83 0.045 0 0 0.039 0.048 3 Plasmacytoid dendritic cells Mesoderm Immune system HB15,BL11 CD83 molecule flag
0
Mm Hs CD86 0.026 0 0 0.012 0.029 7 Plasmacytoid dendritic cells Mesoderm Immune system B7.2,B7-2,CD28LG2 CD86 molecule flag
0
Mm Hs IL3RA 0.008 0 0 0 0.008 3 Plasmacytoid dendritic cells Mesoderm Immune system CD123 interleukin 3 receptor subunit alpha flag
0
Mm Hs CCR7 0.016 0 0 0.042 0.011 10 Plasmacytoid dendritic cells Mesoderm Immune system BLR2,CDw197,CD197,CMKBR7,EBI1 C-C motif chemokine receptor 7 flag
0
Mm Hs CXCR3 0.005 0.045 0 0.005 0.005 4 Plasmacytoid dendritic cells Mesoderm Immune system CKR-L2,CMKAR3,IP10-R,MigR,CD183,GPR9 C-X-C motif chemokine receptor 3 flag
0
Mm Hs ARHGAP9 0.023 0.136 0 0.024 0.022 1 Plasmacytoid dendritic cells Mesoderm Immune system MGC1295,10C Rho GTPase activating protein 9 flag
0
Mm Hs LAMP5 0.005 0.091 0 0.002 0.006 1 Plasmacytoid dendritic cells Mesoderm Immune system dJ1119D9.3,BAD-LAMP,UNC-46,C20orf103 lysosomal associated membrane protein family member 5 flag
0
Mm Hs GPR183 0.019 0.773 0 0.044 0.013 3 Plasmacytoid dendritic cells Mesoderm Immune system EBI2 G protein-coupled receptor 183 flag
0
Mm Hs TNFSF13B 0.011 0.045 0 0.049 0 1 Plasmacytoid dendritic cells Mesoderm Immune system BAFF,THANK,BLYS,TALL-1,TALL1,CD257,TNFSF20 TNF superfamily member 13b flag
0
Mm Hs PTCRA 0.004 0.818 0 0.001 0.003 2 Plasmacytoid dendritic cells Mesoderm Immune system PTA,PT-ALPHA pre T cell antigen receptor alpha flag
0
Mm Hs IGLL1 0.007 0 0 0.036 0.002 2 Plasmacytoid dendritic cells Mesoderm Immune system IGVPB,IGL5,14.1,CD179B,IGLL immunoglobulin lambda like polypeptide 1 Yflag
0
Mm Hs ETV6 0.015 0.182 0 0.048 0.008 2 Plasmacytoid dendritic cells Mesoderm Immune system TEL ETS variant 6 Yflag
0
Mm Hs MAP3K8 0.014 0.318 0.15 0.045 0.007 2 Plasmacytoid dendritic cells Mesoderm Immune system Tpl-2,c-COT,MEKK8,ESTF mitogen-activated protein kinase kinase kinase 8 Yflag
0
Mm Hs FAM129C 0.003 0.636 0 0.003 0.002 2 Plasmacytoid dendritic cells Mesoderm Immune system FLJ39802,BCNP1 family with sequence similarity 129 member C flag
0
Mm Hs SPIB 0.01 0.5 0 0.005 0 5 Plasmacytoid dendritic cells Mesoderm Immune system SPI-B Spi-B transcription factor flag
0
Mm Hs GZMB 0.017 1 0 0.054 0.008 7 Plasmacytoid dendritic cells Mesoderm Immune system CCPI,CGL-1,CSP-B,CGL1,CTSGL1,SECT,CSPB granzyme B flag
0
Mm Hs CXCR4 0.04 0.727 0.05 0.195 0.009 18 Plasmacytoid dendritic cells Mesoderm Immune system LESTR,NPY3R,HM89,NPYY3R,D2S201E,fusin,HSY3RR,CD184 C-X-C motif chemokine receptor 4 Yflag
0
Mm Hs PACSIN1 0.04 0 1 0 0.049 3 Plasmacytoid dendritic cells Mesoderm Immune system SDPI protein kinase C and casein kinase substrate in neurons 1 flag
0
Mm Hs TLR9 0 0 0 0 0 7 Plasmacytoid dendritic cells Mesoderm Immune system CD289 toll like receptor 9 flag
0
Mm Hs IRF7 0.033 1 1 0.022 0.031 4 Plasmacytoid dendritic cells Mesoderm Immune system interferon regulatory factor 7 Yflag
0
Mm Hs CD4 0.009 0.273 0.7 0.017 0.007 9 Plasmacytoid dendritic cells Mesoderm Immune system CD4 molecule Yflag
-1
Mm Hs CLEC4G 0.001 0 0 0 0.001 3 Plasmacytoid dendritic cells Mesoderm Immune system UNQ431,LSECtin C-type lectin domain family 4 member G flag
-1
Mm Hs TLR7 0.001 0 0 0 0 1 Plasmacytoid dendritic cells Mesoderm Immune system toll like receptor 7 flag

Datasets with computationally identified Plasmacytoid dendritic cells

SRA SRS tissue cluster cell type p-value FDR View
SRA636225 SRS2737286 Circulating tumor cells in hepatocellular carcinoma 11 Plasmacytoid dendritic cells 4.82E-7 1.07E-4 view data
SRA645056 SRS2819412 Bone marrow 18 Plasmacytoid dendritic cells 1.56E-4 2.19E-2 view data
SRA550660 SRS2089636 Peripheral blood mononuclear cells 5 Plasmacytoid dendritic cells 6.10E-5 2.03E-2 view data
SRA713577 SRS3363004 Peripheral blood mononuclear cells 12 Plasmacytoid dendritic cells 1.38E-14 4.47E-12 view data
SRA716153 SRS3384792 CD34+ cord blood cells 1 Plasmacytoid dendritic cells 1.92E-8 1.85E-5 view data
SRA779509 SRS3805247 Bone marrow 16 Plasmacytoid dendritic cells 1.39E-5 2.26E-3 view data
SRA779509 SRS3805268 Bone marrow 17 Plasmacytoid dendritic cells 3.25E-13 9.74E-11 view data
SRA779509 SRS3805245 Bone marrow 18 Plasmacytoid dendritic cells 2.25E-13 5.84E-11 view data
SRA716153 SRS3384793 CD34+ cord blood cells 0 Plasmacytoid dendritic cells 2.58E-6 4.44E-4 view data
SRA716153 SRS3384793 CD34+ cord blood cells 4 Plasmacytoid dendritic cells 4.72E-7 9.29E-5 view data
SRA767234 SRS3741870 Tonsil CD14+ cells 11 Plasmacytoid dendritic cells 2.91E-8 7.09E-6 view data
SRA701993 SRS3283678 Bone marrow 0 Plasmacytoid dendritic cells 8.36E-5 4.26E-2 view data
SRA701993 SRS3283678 Bone marrow 2 Plasmacytoid dendritic cells 7.46E-5 4.26E-2 view data
SRA701993 SRS3283675 Spleen 0 Plasmacytoid dendritic cells 1.59E-5 6.28E-3 view data
SRA701993 SRS3283675 Spleen 1 Plasmacytoid dendritic cells 4.20E-5 1.24E-2 view data
SRA701993 SRS3283675 Spleen 4 Plasmacytoid dendritic cells 1.52E-5 6.28E-3 view data
SRA779509 SRS3805263 Bone marrow 18 Plasmacytoid dendritic cells 7.85E-11 1.62E-8 view data
SRA701993 SRS3283677 Bone marrow 0 Plasmacytoid dendritic cells 2.77E-6 4.28E-3 view data
SRA701993 SRS3283677 Bone marrow 3 Plasmacytoid dendritic cells 6.84E-5 3.53E-2 view data
SRA701993 SRS3283677 Bone marrow 6 Plasmacytoid dendritic cells 1.11E-5 8.62E-3 view data
SRA653146 SRS3044250 Spleen 19 Plasmacytoid dendritic cells 1.09E-4 7.89E-3 view data
SRA701993 SRS3283676 Spleen 0 Plasmacytoid dendritic cells 1.81E-5 9.25E-3 view data
SRA701993 SRS3283676 Spleen 4 Plasmacytoid dendritic cells 5.93E-6 6.04E-3 view data
SRA779509 SRS3805266 Bone marrow 16 Plasmacytoid dendritic cells 4.09E-11 1.30E-8 view data
SRA749327 SRS3693912 PBMC 8 Plasmacytoid dendritic cells 1.90E-6 7.02E-4 view data
SRA779509 SRS3805254 Bone marrow 18 Plasmacytoid dendritic cells 1.65E-11 6.79E-9 view data
SRA550660 SRS2089638 Peripheral blood mononuclear cells 6 Plasmacytoid dendritic cells 1.79E-5 3.44E-3 view data
SRA716153 SRS3384795 CD34+ cord blood cells 1 Plasmacytoid dendritic cells 2.98E-7 1.85E-4 view data
SRA701993 SRS3283674 Spleen 0 Plasmacytoid dendritic cells 1.60E-5 3.35E-3 view data
SRA701993 SRS3283674 Spleen 1 Plasmacytoid dendritic cells 1.17E-5 3.29E-3 view data
SRA701993 SRS3283674 Spleen 2 Plasmacytoid dendritic cells 1.94E-6 1.63E-3 view data
SRA653146 SRS3044247 Marrow 9 Plasmacytoid dendritic cells 2.59E-5 2.93E-3 view data
SRA779509 SRS3805252 Bone marrow 16 Plasmacytoid dendritic cells 5.55E-8 1.24E-5 view data
SRA701993 SRS3283679 Spleen 0 Plasmacytoid dendritic cells 1.49E-5 6.28E-3 view data
SRA701993 SRS3283679 Spleen 2 Plasmacytoid dendritic cells 1.60E-4 2.48E-2 view data
SRA701993 SRS3283679 Spleen 4 Plasmacytoid dendritic cells 9.65E-6 6.28E-3 view data
SRA779509 SRS3805259 Bone marrow 17 Plasmacytoid dendritic cells 3.78E-11 9.03E-9 view data
SRA621638 SRS2610283 Bone marrow 8 Plasmacytoid dendritic cells 1.91E-8 4.90E-6 view data
SRA779509 SRS3805265 Bone marrow 13 Plasmacytoid dendritic cells 4.42E-8 6.23E-6 view data
SRA779509 SRS3805255 Bone marrow 20 Plasmacytoid dendritic cells 8.10E-12 2.63E-9 view data
SRA779509 SRS3805256 Bone marrow 16 Plasmacytoid dendritic cells 3.78E-10 1.41E-7 view data
SRA653146 SRS2874278 Bone marrow 12 Plasmacytoid dendritic cells 7.22E-9 1.02E-6 view data
SRA779509 SRS3805258 Bone marrow 16 Plasmacytoid dendritic cells 2.06E-11 5.13E-9 view data