Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Gene expression markers for Principal cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
2
Mm Hs KCNE1 0.001 0 1 0 0.001 1 Principal cells Mesoderm Kidney minK,ISK,JLNS2,LQT5 potassium voltage-gated channel subfamily E regulatory subunit 1 Yflag
1
Mm Hs TACSTD2 0.033 0 0 0.098 0 3 Principal cells Mesoderm Kidney TROP2,GA733-1,EGP-1,M1S1 tumor associated calcium signal transducer 2 Yflag
1
Mm Hs RNF186 0.013 0 0 0.003 0 2 Principal cells Mesoderm Kidney FLJ20225 ring finger protein 186 flag
0
Mm Hs PHACTR1 0.039 0 0.286 0.034 0.04 1 Principal cells Mesoderm Kidney KIAA1733,dJ257A7.2,RPEL1 phosphatase and actin regulator 1 flag
0
Mm Hs CLDN4 0.047 0 0.286 0.128 0.029 5 Principal cells Mesoderm Kidney CPE-R,WBSCR8,hCPE-R,CPETR,CPETR1 claudin 4 flag
0
Mm Hs TBCK 0.006 0 0 0.002 0 2 Principal cells Mesoderm Kidney MGC16169,HSPC302 TBC1 domain containing kinase Yflag
0
Mm Hs AQP2 0.001 0 1 0.001 0 2 Principal cells Mesoderm Kidney aquaporin 2 Yflag
0
Mm GSTT1 0.022 0 0.857 0 0.028 4 Principal cells Mesoderm Kidney glutathione S-transferase theta 1 flag
0
Mm Hs GPRC5B 0.02 0 0 0.01 0.023 1 Principal cells Mesoderm Kidney RAIG-2 G protein-coupled receptor class C group 5 member B flag
0
Mm TMEM178 0.009 NA NA NA NA 1 Principal cells Mesoderm Kidney transmembrane protein 178 flag
0
Mm Hs HES1 0.129 0 0.714 0.146 0.127 4 Principal cells Mesoderm Kidney FLJ20408,HES-1,Hes1,bHLHb39,HRY hes family bHLH transcription factor 1 flag
0
Mm Hs CELSR2 0.019 0 0.286 0 0.023 2 Principal cells Mesoderm Kidney KIAA0279,MEGF3,Flamingo1,CDHF10,ADGRC2,EGFL2 cadherin EGF LAG seven-pass G-type receptor 2 flag
0
Mm Hs STC1 0.005 0 0 0.018 0 2 Principal cells Mesoderm Kidney STC stanniocalcin 1 flag
0
Mm Hs FZD1 0.01 0 0 0.003 0.012 3 Principal cells Mesoderm Kidney DKFZp564G072 frizzled class receptor 1 flag
0
Mm Hs KLK1 0.013 0 0.286 0.008 0.014 7 Principal cells Mesoderm Kidney Klk6 kallikrein 1 Yflag
0
Mm Hs ACER2 0.012 0 0 0 0.014 1 Principal cells Mesoderm Kidney FLJ41587,ALKCDase2,ASAH3L alkaline ceramidase 2 flag
0
Mm Hs AQP4 0.024 0 0 0.006 0.029 9 Principal cells Mesoderm Kidney MIWC aquaporin 4 flag
0
Mm Hs TMEM45B 0.02 0 0 0.016 0 2 Principal cells Mesoderm Kidney BC016153,FLJ40787 transmembrane protein 45B flag
0
Mm Hs AQP3 0.025 0 1 0.071 0.015 8 Principal cells Mesoderm Kidney GIL aquaporin 3 (Gill blood group) Yflag
0
Mm Hs NR3C2 0.003 0 0.286 0.007 0.002 1 Principal cells Mesoderm Kidney MR,MLR nuclear receptor subfamily 3 group C member 2 Yflag
0
Mm Hs AVPR2 0 0 0 0 0 2 Principal cells Mesoderm Kidney V2R,DIR3,DIR arginine vasopressin receptor 2 Yflag
0
Mm Hs SCNN1G 0.002 0 0 0 0 3 Principal cells Mesoderm Kidney ENaCgamma,SCNEG sodium channel epithelial 1 gamma subunit Yflag
0
Mm Hs SCNN1B 0.003 0 0 0.003 0 3 Principal cells Mesoderm Kidney ENaCbeta sodium channel epithelial 1 beta subunit Yflag
0
Mm Hs PTGES 0.013 0 0.429 0.004 0.013 2 Principal cells Mesoderm Kidney MGST-IV,PIG12,MGST1-L1,TP53I12,MGST1L1 prostaglandin E synthase flag
0
Mm Hs TSPAN1 0.028 0 0 0.065 0 2 Principal cells Mesoderm Kidney TSPAN-1,NET-1 tetraspanin 1 flag
0
Mm Hs FXYD4 0.003 0 1 0 0.003 1 Principal cells Mesoderm Kidney CHIF FXYD domain containing ion transport regulator 4 flag
0
Mm Hs HSD11B2 0.004 0 1 0.011 0.002 2 Principal cells Mesoderm Kidney SDR9C3 hydroxysteroid 11-beta dehydrogenase 2 Yflag
-1
Mm Hs PDZK1IP1 0.025 0 1 0.043 0.023 3 Principal cells Mesoderm Kidney DD96,MAP17,SPAP PDZK1 interacting protein 1 flag
-1
Mm Hs TRPV5 0 0 0 0 0 2 Principal cells Mesoderm Kidney CaT2,ECAC1 transient receptor potential cation channel subfamily V member 5 flag
-1
Mm Hs GATA3 0.03 0 1 0.02 0.029 7 Principal cells Mesoderm Kidney HDR GATA binding protein 3 Yflag
-1
Mm Hs FZD7 0.003 0 0.143 0.001 0.002 1 Principal cells Mesoderm Kidney FzE3 frizzled class receptor 7 flag
-1
Mm Hs CDH16 0.004 0 1 0.001 0.004 2 Principal cells Mesoderm Kidney cadherin 16 flag
-1
Mm Hs ADGRG1 0.045 0 1 0.021 0.05 3 Principal cells Mesoderm Kidney TM7LN4,TM7XN1,GPR56 adhesion G protein-coupled receptor G1 Yflag
-1
Mm Hs TSPAN8 0.047 0 0 0.048 0 4 Principal cells Mesoderm Kidney CO-029,TM4SF3 tetraspanin 8 flag
-1
Mm Hs CDO1 0.036 0 0.857 0.012 0.041 4 Principal cells Mesoderm Kidney cysteine dioxygenase type 1 flag
-1
Mm Hs LGALS3 0.164 0 1 0.309 0.128 3 Principal cells Mesoderm Kidney MAC-2,GALIG,LGALS2 galectin 3 flag
-2
Mm Hs TMEM229A 0.017 0 0 0 0 1 Principal cells Mesoderm Kidney transmembrane protein 229A flag
-2
Mm Hs PELI2 0.005 0 0.429 0.002 0.006 1 Principal cells Mesoderm Kidney pellino E3 ubiquitin protein ligase family member 2 flag
-2
Mm Hs SLC2A9 0 0 0 0 0 1 Principal cells Mesoderm Kidney Glut9,GLUTX,URATv1 solute carrier family 2 member 9 Yflag
-2
Mm Hs L1CAM 0.018 0 0.429 0.002 0.021 5 Principal cells Mesoderm Kidney CD171,HSAS1,SPG1,HSAS,MIC5 L1 cell adhesion molecule Yflag
-2
Mm Hs NPNT 0.017 0 0.857 0.009 0.019 2 Principal cells Mesoderm Kidney EGFL6L,POEM nephronectin flag
-2
Mm Hs APELA 0.004 0 1 0.002 0.004 1 Principal cells Mesoderm Kidney Ende,ELA,tdl apelin receptor early endogenous ligand flag
-2
Mm Hs KCNJ1 0.002 0 1 0.001 0.002 2 Principal cells Mesoderm Kidney Kir1.1,ROMK1 potassium voltage-gated channel subfamily J member 1 Yflag
-2
Mm Hs SCNN1A 0.008 0 0 0.011 0 4 Principal cells Mesoderm Kidney ENaCalpha,SCNN1 sodium channel epithelial 1 alpha subunit Yflag

Datasets with computationally identified Principal cells

SRA SRS tissue cluster cell type p-value FDR View
SRA635314 SRS2727267 Whole kidney 14 Principal cells 1.56E-22 1.55E-19 view data
SRA635314 SRS2727265 Whole kidney 8 Principal cells 1.21E-19 1.70E-16 view data
SRA653146 SRS3044242 Kidney 9 Principal cells 1.54E-25 6.79E-23 view data
SRA635314 SRS2727268 Whole kidney 16 Principal cells 1.57E-20 1.16E-17 view data
SRA653146 SRS3044249 Kidney 13 Principal cells 3.47E-30 2.33E-27 view data
SRA635314 SRS2727266 Whole kidney 12 Principal cells 4.69E-22 3.30E-19 view data
SRA662115 SRS2998547 Kidney 7 Principal cells 3.86E-20 1.07E-17 view data