Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Description: Sertoli cells are the somatic cells of the testis that are essential for testis formation and spermatogenesis.

Gene expression markers for Sertoli cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
2
Mm Hs DIAPH2 0.005 0 0 0.008 0.004 1 Sertoli cells Mesoderm Reproductive POF2,DIA2 diaphanous related formin 2 Yflag
2
Mm Hs HSPBAP1 0.005 0 0 0.01 0.004 1 Sertoli cells Mesoderm Reproductive FLJ22623,PASS1 HSPB1 associated protein 1 flag
1
Mm Hs CLU 0.168 0 1 0.216 0.161 2 Sertoli cells Mesoderm Reproductive SGP-2,SP-40,TRPM-2,KUB1,CLU2,CLI,APOJ clusterin flag
1
Mm Hs NOTCH2 0.096 0 0.605 0.02 0.113 2 Sertoli cells Mesoderm Reproductive notch 2 Yflag
1
Mm Hs PRND 0 0 0 0.002 0 1 Sertoli cells Mesoderm Reproductive DPL,dJ1068H6.4,DOPPEL,PrPLP prion like protein doppel flag
0
Mm Hs CXCL12 0.07 0 0 0.027 0.082 3 Sertoli cells Mesoderm Reproductive SCYB12,SDF-1a,SDF-1b,PBSF,TLSF-a,TLSF-b,TPAR1,SDF1A,SDF1B,SDF1 C-X-C motif chemokine ligand 12 Yflag
0
Mm Hs STAR 0.001 0 0 0 0 3 Sertoli cells Mesoderm Reproductive StAR,STARD1 steroidogenic acute regulatory protein Yflag
0
Mm Hs WFDC2 0.056 0 0 0.094 0 3 Sertoli cells Mesoderm Reproductive HE4,WAP5,dJ461P17.6,EDDM4 WAP four-disulfide core domain 2 flag
0
Mm Hs PHF7 0.018 0 0 0.062 0.009 2 Sertoli cells Mesoderm Reproductive NYD-SP6,HSPC226 PHD finger protein 7 flag
0
Mm TSX 0 NA NA NA NA 1 Sertoli cells Mesoderm Reproductive testis specific X-linked gene flag
0
Mm Hs ANKRD7 0.01 0 0 0.049 0.003 1 Sertoli cells Mesoderm Reproductive TSA806 ankyrin repeat domain 7 flag
0
Mm Hs NXF3 0 0 0 0.001 0 1 Sertoli cells Mesoderm Reproductive nuclear RNA export factor 3 flag
0
Mm Hs GBA2 0.001 0 0 0.001 0.001 1 Sertoli cells Mesoderm Reproductive KIAA1605,AD035,DKFZp762K054,SPG46 glucosylceramidase beta 2 Yflag
0
Mm Hs PADI2 0.007 0 0 0.008 0.007 2 Sertoli cells Mesoderm Reproductive KIAA0994,PDI2 peptidyl arginine deiminase 2 flag
0
Mm Hs ABCG8 0.002 0 0 0 0.003 2 Sertoli cells Mesoderm Reproductive GBD4 ATP binding cassette subfamily G member 8 Yflag
0
Mm Hs STIM1 0.01 0 0 0.001 0 1 Sertoli cells Mesoderm Reproductive GOK,D11S4896E stromal interaction molecule 1 Yflag
0
Mm Hs CTSA 0.104 0 0 0.024 0.122 2 Sertoli cells Mesoderm Reproductive GSL,PPGB cathepsin A Yflag
0
Mm Hs PFKFB3 0.006 0 0 0.007 0.006 1 Sertoli cells Mesoderm Reproductive 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 flag
0
Mm Hs HSD17B1 0.002 0 0.658 0.005 0 2 Sertoli cells Mesoderm Reproductive MGC138140,SDR28C1,EDH17B2 hydroxysteroid 17-beta dehydrogenase 1 flag
0
Mm Hs CD46 0.014 0 0 0.079 0.001 4 Sertoli cells Mesoderm Reproductive TRA2.10,MGC26544,MIC10 CD46 molecule Yflag
0
Mm Hs SOX9 0.086 0 0 0.032 0 8 Sertoli cells Mesoderm Reproductive SRA1,CMD1,CMPD1 SRY-box 9 Yflag
0
Mm Hs BCAR3 0.007 0 0 0.006 0.007 1 Sertoli cells Mesoderm Reproductive SH2D3B,AND-34 BCAR3, NSP family adaptor protein flag
0
Mm Hs NR1H2 0.039 0 0 0.055 0.033 1 Sertoli cells Mesoderm Reproductive NER,NER-I,RIP15,LXR-b,LXRb nuclear receptor subfamily 1 group H member 2 flag
0
Mm Hs EPS8 0.02 0 0.105 0.041 0.015 1 Sertoli cells Mesoderm Reproductive epidermal growth factor receptor pathway substrate 8 Yflag
0
Mm Hs SLC16A3 0.033 0 0 0.061 0 2 Sertoli cells Mesoderm Reproductive solute carrier family 16 member 3 flag
0
Mm Hs PRLR 0.013 0 0 0.011 0.014 6 Sertoli cells Mesoderm Reproductive prolactin receptor Yflag
0
Mm Hs RXRB 0.009 0 0 0.001 0 1 Sertoli cells Mesoderm Reproductive NR2B2,H-2RIIBP,RCoR-1 retinoid X receptor beta flag
0
Mm Hs FSHR 0 0 0 0 0 2 Sertoli cells Mesoderm Reproductive FSHRO,LGR1,ODG1 follicle stimulating hormone receptor Yflag
0
Mm Hs MSI1 0.022 0 0.184 0.025 0.021 3 Sertoli cells Mesoderm Reproductive musashi RNA binding protein 1 flag
0
Mm Hs CD55 0.037 0 0 0.126 0.02 7 Sertoli cells Mesoderm Reproductive TC,CROM,DAF CD55 molecule (Cromer blood group) Yflag
0
Mm Hs SERPING1 0.066 0 0 0.099 0 3 Sertoli cells Mesoderm Reproductive C1IN,C1-INH,HAE1,HAE2,C1NH serpin family G member 1 Yflag
0
Mm Hs SERPINB9 0.018 0 0 0.033 0 3 Sertoli cells Mesoderm Reproductive CAP3,PI9 serpin family B member 9 flag
0
Mm SERPINA3N 0.009 NA NA NA NA 1 Sertoli cells Mesoderm Reproductive serine (or cysteine) peptidase inhibitor, clade A, member 3N flag
0
Mm Hs OCLN 0.013 0 0 0 0.016 2 Sertoli cells Mesoderm Reproductive PPP1R115 occludin Yflag
0
Mm Hs CLDN11 0.059 0 0.474 0.042 0.064 2 Sertoli cells Mesoderm Reproductive OSP,OTM claudin 11 flag
0
Mm Hs GATA6 0.019 0 0.605 0.005 0.02 3 Sertoli cells Mesoderm Reproductive GATA binding protein 6 Yflag
0
Mm Hs MAFB 0.053 0 0 0.059 0.053 6 Sertoli cells Mesoderm Reproductive KRML MAF bZIP transcription factor B Yflag
0
Mm Hs DES 0.021 0 0 0.009 0.023 11 Sertoli cells Mesoderm Reproductive CMD1I,CSM1,CSM2 desmin Yflag
0
Mm Hs INHA 0.006 0 1 0.013 0.003 3 Sertoli cells Mesoderm Reproductive inhibin subunit alpha flag
0
Mm Hs NF2 0.016 0 0 0.044 0.008 4 Sertoli cells Mesoderm Reproductive merlin,ACN,SCH,BANF neurofibromin 2 Yflag
0
Mm CCL9 0.037 0 0 0 0.044 6 Sertoli cells Mesoderm Reproductive chemokine (C-C motif) ligand 9 flag
0
Mm Hs HES5 0.036 0 0 0.001 0.042 3 Sertoli cells Mesoderm Reproductive bHLHb38 hes family bHLH transcription factor 5 flag
0
Mm KITL 0.041 0 0.553 0 0.05 3 Sertoli cells Mesoderm Reproductive kit ligand flag
0
Mm Hs MEIG1 0.018 0 0.026 0.014 0.02 4 Sertoli cells Mesoderm Reproductive bA2K17.3,SPATA39 meiosis/spermiogenesis associated 1 flag
0
Mm Hs GAMT 0.051 0 0.816 0.066 0.044 3 Sertoli cells Mesoderm Reproductive PIG2,TP53I2 guanidinoacetate N-methyltransferase Yflag
0
Mm Hs FAS 0.011 0 0 0.015 0.011 4 Sertoli cells Mesoderm Reproductive CD95,APO-1,FAS1,APT1,TNFRSF6 Fas cell surface death receptor Yflag
0
Mm Hs GDNF 0 0 0 0 0 1 Sertoli cells Mesoderm Reproductive ATF1,ATF2,HFB1-GDNF glial cell derived neurotrophic factor Yflag
0
Mm Hs AR 0.013 0 0 0.002 0.016 6 Sertoli cells Mesoderm Reproductive AIS,NR3C4,SMAX1,HUMARA,DHTR,SBMA androgen receptor Yflag
0
Mm Hs DHH 0.002 0 0.711 0 0.001 2 Sertoli cells Mesoderm Reproductive HHG-3,MGC35145 desert hedgehog Yflag
0
Mm Hs GATA4 0.008 0 0.711 0.005 0.006 6 Sertoli cells Mesoderm Reproductive GATA binding protein 4 Yflag
0
Mm Hs GATA1 0.008 0 0 0.018 0.006 3 Sertoli cells Mesoderm Reproductive ERYF1,NFE1,GATA-1 GATA binding protein 1 Yflag
0
Mm Hs SHBG 0.001 0 0 0.003 0 1 Sertoli cells Mesoderm Reproductive ABP,TEBG,MGC126834,MGC138391 sex hormone binding globulin flag
0
Mm Hs INHBB 0.005 0 0.711 0.003 0.003 2 Sertoli cells Mesoderm Reproductive inhibin subunit beta B flag
0
Mm Hs AMH 0.004 0 0.947 0.015 0 2 Sertoli cells Mesoderm Reproductive MIS anti-Mullerian hormone Yflag
0
Mm GSTM6 0.006 0 0.947 0 0.005 1 Sertoli cells Mesoderm Reproductive glutathione S-transferase, mu 6 flag
0
Mm Hs SCX 0.003 0 0 0.002 0 1 Sertoli cells Mesoderm Reproductive bHLHa48,bHLHa41,SCXA,SCXB scleraxis bHLH transcription factor flag
0
Mm Hs SEMA5B 0.003 0 0 0 0 1 Sertoli cells Mesoderm Reproductive SemG,KIAA1445,FLJ10372,SEMAG semaphorin 5B flag
0
Mm Hs AMHR2 0.002 0 0.474 0 0.001 1 Sertoli cells Mesoderm Reproductive MISR2,MISRII anti-Mullerian hormone receptor type 2 Yflag
0
Mm Hs HSD17B3 0.002 0 0.737 0.003 0 2 Sertoli cells Mesoderm Reproductive SDR12C2 hydroxysteroid 17-beta dehydrogenase 3 Yflag
0
Mm Hs MRO 0.004 0 0.789 0 0.003 1 Sertoli cells Mesoderm Reproductive FLJ30140,C18orf3 maestro flag
0
Mm Hs WNT6 0.007 0 0 0.005 0 1 Sertoli cells Mesoderm Reproductive Wnt family member 6 flag
0
Mm Hs TMEM184A 0.006 0 0 0 0 1 Sertoli cells Mesoderm Reproductive MGC9712,SDMG1 transmembrane protein 184A flag
0
Mm ETD 0.001 0 0.737 0 0 1 Sertoli cells Mesoderm Reproductive embryonic testis differentiation flag
0
Hs KITLG 0.001 0 0 0.006 0 4 Sertoli cells Mesoderm Reproductive SCF,Kitl,KL-1,FPH2,SLF,DFNA69 KIT ligand Yflag
0
Mm RHOX8 0.002 NA NA NA NA 1 Sertoli cells Mesoderm Reproductive reproductive homeobox 8 flag
0
Mm Hs CST9 0.002 0 0.921 0 0.001 1 Sertoli cells Mesoderm Reproductive CTES7A cystatin 9 flag
0
Mm DEFB19 0.003 0 1 0 0.002 1 Sertoli cells Mesoderm Reproductive defensin beta 19 flag
0
Mm CST12 0.003 0 1 0 0.001 1 Sertoli cells Mesoderm Reproductive cystatin 12 flag
0
Mm Hs AARD 0.012 0 1 0.014 0.01 1 Sertoli cells Mesoderm Reproductive LOC441376,C8orf85 alanine and arginine rich domain containing protein flag
0
Mm Hs WT1 0.01 0 0 0.023 0 10 Sertoli cells Mesoderm Reproductive WIT-2,AWT1,NPHS4,GUD Wilms tumor 1 Yflag
0
Hs TF 0.004 0 0 0.018 0 2 Sertoli cells Mesoderm Reproductive PRO1557,PRO2086 transferrin Yflag
-1
Hs FASLG 0 0 0 0.001 0 1 Sertoli cells Mesoderm Reproductive FasL,CD178,APT1LG1,TNFSF6 Fas ligand Yflag

Datasets with computationally identified Sertoli cells

SRA SRS tissue cluster cell type p-value FDR View
SRA645836 SRS2823453 Testis 8 Sertoli cells 3.25E-14 5.78E-11 view data
SRA742982 SRS3565399 Testis 1 Sertoli cells 1.48E-12 1.65E-9 view data
SRA742982 SRS3565399 Testis 4 Sertoli cells 6.89E-12 4.38E-9 view data
SRA742982 SRS3565399 Testis 6 Sertoli cells 2.56E-11 1.26E-8 view data
SRA742982 SRS3565399 Testis 7 Sertoli cells 8.22E-14 1.30E-10 view data
SRA742982 SRS3565399 Testis 8 Sertoli cells 1.16E-9 5.17E-7 view data
SRA742982 SRS3565399 Testis 9 Sertoli cells 2.82E-12 2.51E-9 view data
SRA742982 SRS3565399 Testis 14 Sertoli cells 3.63E-12 2.69E-9 view data
SRA742982 SRS3565399 Testis 17 Sertoli cells 1.45E-11 8.05E-9 view data
SRA742982 SRS3565399 Testis 19 Sertoli cells 8.76E-14 1.30E-10 view data
SRA742982 SRS3565401 Testis 1 Sertoli cells 6.77E-12 8.04E-9 view data
SRA742982 SRS3565401 Testis 4 Sertoli cells 3.22E-11 2.29E-8 view data
SRA742982 SRS3565401 Testis 6 Sertoli cells 2.57E-13 9.15E-10 view data
SRA742982 SRS3565401 Testis 7 Sertoli cells 5.51E-13 9.81E-10 view data
SRA742982 SRS3565401 Testis 8 Sertoli cells 6.68E-6 1.90E-3 view data
SRA742982 SRS3565401 Testis 15 Sertoli cells 1.54E-6 5.48E-4 view data
SRA742982 SRS3565401 Testis 17 Sertoli cells 5.16E-10 3.06E-7 view data
SRA742982 SRS3565397 Testis 2 Sertoli cells 8.37E-13 1.22E-9 view data
SRA742982 SRS3565397 Testis 3 Sertoli cells 1.13E-12 1.22E-9 view data
SRA742982 SRS3565397 Testis 4 Sertoli cells 1.21E-10 7.53E-8 view data
SRA742982 SRS3565397 Testis 5 Sertoli cells 1.30E-12 1.22E-9 view data
SRA742982 SRS3565397 Testis 8 Sertoli cells 1.14E-11 8.54E-9 view data
SRA742982 SRS3565397 Testis 12 Sertoli cells 1.27E-12 1.22E-9 view data
SRA742982 SRS3565397 Testis 17 Sertoli cells 2.94E-6 9.15E-4 view data
SRA742982 SRS3565409 Testis 1 Sertoli cells 1.28E-12 1.10E-9 view data
SRA742982 SRS3565409 Testis 3 Sertoli cells 3.33E-11 2.37E-8 view data
SRA742982 SRS3565409 Testis 7 Sertoli cells 1.02E-12 1.09E-9 view data
SRA742982 SRS3565409 Testis 9 Sertoli cells 3.74E-10 2.28E-7 view data
SRA742982 SRS3565409 Testis 12 Sertoli cells 1.45E-4 2.58E-2 view data
SRA742982 SRS3565409 Testis 18 Sertoli cells 1.24E-6 3.78E-4 view data
SRA645836 SRS2823483 Testis 0 Sertoli cells 6.56E-14 3.74E-11 view data
SRA645836 SRS2823483 Testis 2 Sertoli cells 9.53E-15 9.05E-12 view data
SRA645836 SRS2823483 Testis 3 Sertoli cells 2.31E-14 1.64E-11 view data
SRA645836 SRS2823483 Testis 7 Sertoli cells 8.53E-14 4.05E-11 view data
SRA645836 SRS2823483 Testis 8 Sertoli cells 6.06E-17 1.73E-13 view data
SRA645836 SRS2823483 Testis 10 Sertoli cells 5.57E-6 8.81E-4 view data
SRA645836 SRS2823483 Testis 11 Sertoli cells 2.12E-10 6.05E-8 view data
SRA645779 SRS2823375 Testis 10 Sertoli cells 1.36E-15 2.90E-13 view data